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Assessment of global LV systolic function has an important role in assessing the prognosis of a variety of cardiac diseases, and also influences treatment strategies. 1 The most widely used parameter is LVEF, and this is commonly obtained by echocardiography.
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Global longitudinal strain assesses the function of longitudinally orientated myofibers, which are most vulnerable to myocardial disease because of their subendocardial location; GCS assesses circumferential myofibers, which are predominantly located in the midmyocardial wall and are typically affected in more clinically significant myocardial .
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